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The approval is based on data from a post-approval clinical study, published in the New England Journal of Medicine on 11 November 2023, which demonstrated that semaglutide (2.4mg once weekly by subcutaneous injection for up to five years) lowered the incidence of major adverse cardiovascular events compared with placebo
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Studenski SA, Peters KW, Alley DE, Cawthon PM, McLean RR, Harris TB, Ferrucci L, Guralnik JM, Fragala MS, Kenny AM, et al